Bjarke Feenstra

Bjarke Feenstra

Contact

Bjarke Feenstra, Senior Researcher, Department of Epidemiology Research
T. +45 32683852 @. fee@ssi.dk

Senior Researcher

Research Areas

I am interested in understanding how genetic variation affects health and disease with a focus on pregnancy-related outcomes (birthweight and gestational duration) and selected childhood diseases. I often use the genome-wide association study (GWAS) approach, but my projects also include other types of data, such as metabolomics profiles. In terms of childhood diseases, I am particularly interested in 1) the gastrointestinal disorder pyloric stenosis, and 2) febrile seizures.


Education   
2006  PhD in Statistical Genetics. The Royal Veterinary and Agricultural University of Denmark.  
2002  MSc in Biology and Statistics. University of Copenhagen. 
1997  BSc in Biology. University of Copenhagen. 

Employment  
2011–  Senior Researcher, Dept. of Epidemiology Research, SSI. 
2007–2011  Research Scientist, Dept. of Epidemiology Research, SSI. 
2006–2007  Research Scientist, Dept. of Statistics, deCODE genetics, Iceland. 
2004–2005  Visiting Scientist, Dept. of Biostatistics, Johns Hopkins University, Baltimore (4 months). 
2003–2005 
Statistics Instructor. The Royal Veterinary and Agricultural University of Denmark. 
2002  Visiting Research Assistant, Dept. of Biostatistics, Columbia University, New York (6 months). 
1999 – 2001  Assistant Editor of Biology, Danish National Encyclopedia. 

 Professional Activities and Leadership Positions
2016-
Research Group Leader, Dept. of Epidemiology Research, SSI. 
2007-  Project leadership on numerous GWAS projects. 

Prizes and Honours
2012  The Thorvald Madsen Prize 

International Collaborations
A number of collaborative projects with the Early Growth Genetics (EGG) consortium and the iPSYCH consortium. Many international collaborations, e.g., for replication of genetic association findings or functional follow-up experiments. 
 

Selected recent publications 
Liu X, Helenius D, Skotte L, …, Buil A, Feenstra B. Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration. bioRxiv 2018; 423897, https://doi.org/10.1101/423897  
Fadista J, Skotte L, …, Feenstra B. Genome-wide meta-analysis identifies BARX1 and EML4-MTA3 as new loci associated with infantile hypertrophic pyloric stenosis. Human Molecular Genetics 2018; ddy347, https://doi.org/10.1093/hmg/ddy347 
Beaumont RN, Warrington NM, …, Evans DM*, Lawlor DA*, Feenstra B*, Freathy RM*. Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Human Molecular Genetics 2018; 27, 742-756, https://doi.org/10.1093/hmg/ddx429 *Shared last author  
Zhang G, Feenstra B, …, Muglia LJ. Genetic Associations with Gestational Duration and Spontaneous Preterm Birth. New England Journal of Medicine 2017; 377, 1156-
1167, https://doi.org/10.1056/NEJMoa1612665 

Feenstra B, …, Hviid A. Common variants associated with general and MMR vaccine-related febrile seizures. Nature Genetics 2014; 46: 1274-1282, https://doi.org/10.1038/ng.3129