Experimental infection models

SSI has state of the art laboratories and animal facilities. We offer design, planning and execution of in vivo experimental infection studies. These models can be used for studying host pathogen interactions, host responses, bacterial virulence and antibiotic treatment.

Updated 24 October 2019

Murine infection models

Peritonitis/Sepsis
Thigh infection
Urinary tract infection
Skin infection
Pneumonia
Fungal sepsis
Colon colonization

Examples of human pathogens used infection models

Peritonitis/sepsis model

Staphylococcus aureus (MRSA)
Streptococcus pneumoniae
Streptococcus pyogenes
Escherichia coli (ESBL)
Klebsiella spp.
Enterobacter spp.
Proteus mirabilis
Pseudomonas aeruginosa
Enterococcus faecalis

Skin infection model

Staphylococcus aureus (MRSA)
Streptococcus pyogenes
Pseudomonas aeruginosa
Candida Albicans

Urinary tract infection model

Escherichia coli (ESBL)
Klebsiella spp.
Proteus spp.

Pneumonia model

Staphylococcus aureus (MRSA)
Streptococcus pneumoniae
Klebsiella pneumoniae
Pseudomonas aeruginosa

Temaer

Antimicrobial evaluation — Antimicrobial evaluation

Statens Serum Institut (SSI) has state of the art laboratories and animal facilities. We offer design, planning and execution of in vitro and in vivo studies.

Assay design and development — Assay design and development

At Statens Serum Institut (SSI) we have a long-term experience in quantitative detection of virus and virus-specific antibodies using the haemagglutination (HA) assay and the haemagglutination inhibition (HAI) assay.

Detection of viruses — Detection of viruses

The unbiased DNA microarray testing has emerged as a promising new technology for broad-spectrum virus detection (metagenomic diagnostic), making it possible to test for the presence of thousands of viruses simultaneously without having a clear predetermination of what to look for. This is convenient e.g. in diagnostic for disease syndromes, in hematological patients, in travellers with exotic virus, and difficult to diagnose patients. We have developed a microarray platform, Pan-Virus Array.

Development of monoclonal and polyclonal antibodies — Development of monoclonal and polyclonal antibodies

Statens Serum Instititut (SSI) has about 35 years of experience in developing and producing monoclonal antibodies and more than 100 years of experience in production of polyclonal antibodies. SSI uses different species of animals for this purpose.

Carina Vingsbo Lundberg

Contact

Carina Vingsbo Lundberg , Bakterier, parasitter og svampe / Antibiotikaresistens og Præklinisk Forsk
T. +45 32688209 @. cvl@ssi.dk View profile