Katrine Grimstrup Joensen

Katrine Grimstrup Joensen

Contact

Katrine Grimstrup Joensen
T. +45 32688965 @. knj@ssi.dk

Research area

Research within the development of Next-generation sequencing (NGS)-based surveillance and outbreak detection of food borne pathogenic bacteria.  Primarily by analysis of whole-genome sequence (WGS) data of Campylobacter, but also including WGS-based projects on Shiga toxin-producing E. coli (STEC), and C. difficile.

Pubmed link

https://www.ncbi.nlm.nih.gov/pubmed/?term=joensen-kg

Responsibilities

  • Development and implementation of whole-genome sequencing (WGS) -based typing methods for use in national surveillance of foodborne pathogenic bacteria
    • primarily for Campylobacter, STEC, (C. difficile)
  • Development, implementation and maintenance of databases for extracting genetic markers, e.g. virulence genes, serotype-specific genes and resistance markers, for surveillance. 
  • Surveillance and outbreak detection 
    • within STEC, Listeria and Campylobacter

Publikationer

  • Joensen KG, Tetzschner AM, Iguchi A, Aarestrup FM, Scheutz F. Rapid and Easy In Silico Serotyping of Escherichia coli Isolates by Use of Whole-Genome Sequencing Data. J Clin Microbiol. 2015 Aug;53(8):2410-26. doi:10.1128/JCM.00008-15. Epub 2015 May 13. 
  • Joensen KG, Kuhn KG, Müller L, Björkman JT, Torpdahl M, Engberg J, Holt HM, Nielsen HL, Petersen AM, Ethelberg S, Nielsen EM. Whole-genome sequencing of Campylobacter jejuni isolated from Danish routine human stool samples reveals surprising degree of clustering. Clin Microbiol Infect. 2018Feb;24(2):201.e5-201.e8. doi: 10.1016/j.cmi.2017.07.026.
  • Joensen KG, Engsbro ALØ, Lukjancenko O, Kaas RS, Lund O, Westh H, AarestrupFM. Evaluating next-generation sequencing for direct clinical diagnostics in diarrhoeal disease. Eur J Clin Microbiol Infect Dis. 2017 Jul;36(7):1325-1338.doi: 10.1007/s10096-017-2947-2. 
  • Joensen KG, Scheutz F, Lund O, Hasman H, Kaas RS, Nielsen EM, Aarestrup FM. Real-time whole-genome sequencing for routine typing, surveillance, and outbreak detection of verotoxigenic Escherichia coli. J Clin Microbiol. 2014May;52(5):1501-10. doi: 10.1128/JCM.03617-13. Epub 2014 Feb 26.
  • Zschach H, Joensen KG, Lindhard B, Lund O, Goderdzishvili M, Chkonia I, JgentiG, Kvatadze N, Alavidze Z, Kutter EM, Hasman H, Larsen MV. What Can We Learn froma Metagenomic Analysis of a Georgian acteriophage Cocktail? Viruses. 2015 Dec12;7(12):6570-89. doi: 10.3390/v7122958.