Immune repertoire profiling especially immunoglobulin sequencing in the context of diseases, including chronic lymphocytic leukemia, cancers and multiple sclerosis.
- Full-length cDNA library construction (tagged with DNA-barcode) for next generation sequencing
- Analysis of immunoglobulin enrichment
- Generation and characterization of human monoclonal antibodies from vaccinated persons or patient samples
- Recombinant human Ig construction and expression by molecular cloning and expression