Ramona Trebbien

Research area

Evolution of influenza virus in relation to; pathogenicity, antiviral resistance, host factors, receptor binding, effect on antigenicity in relation to vaccine effectiveness etc.

Antibody response against influenza virus after vaccination and infection amongst patients in specific risk groups.

Mechanisms behind zoonotic transmission of influenza virus between different hosts.

Evolution and disease burden of Respiratory Syncytial Virus (RSV).

Responsibilities

Responsible for the National Influenza Center for WHO (DK), which is in charge of the national virological surveillance of influenza virus in Denmark. As well as national surveillance of Respiratory Syncytial Virus (RSV). The laboratory is also national referencelaboratory for avian influenza and Newcastle disease virus (NDV), furthermore the following veterinary viruses; swine influenza virus, porcine reproductive and respiratory syndrome virus (PRRSV), infectious laryngotracheitis virus (ILT), canine distemper virus (CDV), Aleutian mink disease virus (ADV), and Rabbit hemorragic disease virus (RDHV).

Partner fra Statens Serum Institut i FluZooMark projektet, der omhandler zoonotisk influenza.

Publications

• Hansen CH, Midgley SE, Fischer TK. Review of global emergence of enterovirus D68 (EV-D68). Lancet Infectious Diseases 2016: S1473-3099(15)00543-5.

• Nielsen NM, Midgley S, Nielsen AY, Christiansen CB, Fischer TK. Severe Human Parechovirus infections in infants and the role of older siblings. American Journal of Epidemiology 2016; 183: 664-70.

• Barnadas C, Midgley SE, Skov MN, Jensen L, Poulsen MW, Fischer TK. An enhanced Enterovirus surveillance system allows identification and characterization of rare and emerging respiratory enteroviruses in Denmark, 2015-16. Journal of Clinical Virology 2017; 93:40-44.

• Midgley SE, Nielsen AG, Trebbien R, Poulsen MW, Andersen PH, Fischer TK. Co-circulation of multiple subtypes of enterovirus A71 (EV- A71) genotype C, including novel recombinants characterised by use of whole genome sequencing (WGS), Denmark 2016. Euro Surveillance 2017;22(26):pii=30565.

• Broberg EK, Benedetto S, Josep J, the EU/EEA Member State contributors. Upsurge in echovirus 30 detections in five EU/EEA countries, April to September, 2018. Euro Surveill. 2018;23(44):pii=1800537.